A major pharmaceutical company in the Midwest United States came to us with a critical production challenge: keeping a broth with 5% cell solution at a uniform cold temperature—without damaging the cells.
The Challenge:
Traditional mechanical agitators risked damaging the cells due to excessive shear, making them unsuitable for this sensitive application. The customer needed a solution that would maintain uniform cooling while ensuring gentle movement of the cell culture.
Our Solution:
We recommended our hygienic in-tank eductor (Hygienic 3" TLA) to provide the necessary low-shear circulation within the tank. Computational Fluid Dynamics (CFD) modeling confirmed that our pressure and flow rate recommendations achieved the required net movement—keeping the broth at an even, cold temperature without compromising cell integrity.
Jacoby-Tarbox TLA's provided this Pharma company efficient, uniform cooling and optimal cell preservation, a true testament as to why low-shear in-tank eductors are the ideal solution for sensitive biopharma processes. To learn more about eductors and CFD analysis, click here.
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